• Skip navigation
  • Skip to navigation
  • Skip to the bottom
Simulate organization breadcrumb open Simulate organization breadcrumb close
Interdisciplinary Center for Clinical Research
  • FAUTo the central FAU website
  1. Friedrich-Alexander-Universität
  2. Faculty of Medicine
  • Universitätsklinikum
  • Life@FAU
  • IZKF-Tool
  • ELAN-Tool
  1. Friedrich-Alexander-Universität
  2. Faculty of Medicine

Interdisciplinary Center for Clinical Research

Navigation Navigation close
  • IZKF
    • Structure
    • Committees
    • IZKF Administrative Office
    • Other IZKF
    • IZKF publications
    Portal IZKF Erlangen
  • Advanced projects
    • Programme
    • Application Procedure
    • Current projects
    • Project Handling
    Portal Advanced projects
  • Juniors
    • Jochen-Kalden-Funding Programme
    • Junior Projects
    • Clinician Scientist Programme
    • Laboratory Rotations
    • MD-Thesis Scholarships
    • IZKF Research Training Group
    • IZKF Publication Award for Young Scientists
    Portal Juniors
  • ELAN
    • Programme
    • Application Procedure
    • Current projects
    • Project Handling
    Portal ELAN
  • Central projects
    • Special Programmes
    • Visiting Professor Programme
    • Bridging Projects
    • IZKF-Symposium
    Portal Central projects
  1. Home
  2. Juniors
  3. Junior Projects
  4. Current Projects
  5. Infection and Immunology

Infection and Immunology

In page navigation: Juniors
  • Jochen-Kalden-Funding Programme
    • Application procedure
    • N5 Organ crosstalks in IMIDs (Günther)
    • N6 Rare glomerular diseases (Müller-Deile)
    • N7 Forging neural cell identity (Karow)
    • N8 Lysosomal dysfunction in glia (Zunke)
    • Archive Junior Research Groups
      • Junior Research Group 1, Dr. Ceppi
      • Junior Research Group 2, Dr. Dulin
      • Junior Research Group 2, Prof. Titze
      • Junior Research Group 3, Prof. Winner
  • Junior Projects
    • Application Procedure
      • Call for proposals: Junior Projects 2023
    • Current Projects
      • Infection and Immunology
      • Oncology
      • Neurosciences
      • Renal and Vascular Research
      • Further projects
      • Archive Junior Projects
    • Project Handling
  • Clinician Scientist Programme
    • Application procedure
      • Admission into the Clinician Scientist Programme
      • IZKF rotation position for CSP Step 2
    • Participants
    • TOPeCS Funding
    • Alumni
  • Laboratory Rotations
    • Application procedure
    • Current Laboratory Rotations
    • Project Handling
  • MD-Thesis Scholarships
    • Application procedure
    • Current Scholarhip Holders
  • IZKF Research Training Group
    • Application procedure
    • Events
      • Jour Fixe
      • Seminars
      • IZKF Postgraduate Workshop
        • IZKF Postgraduate Workshop 2018
        • IZKF Postgraduate Workshop 2022
      • IZKF-Retreat
        • IZKF-Retreat 2018
  • IZKF Publication Award for Young Scientists
    • Announcement Publication Award for Young Scientists 2022

Infection and Immunology

J87: Stefan Uderhardt, Department of Medicine 3
Stromal Network Communication in the Regulation of Immune Homeostasis

Main Research: Immunology and Infection

Term: 01.01.2021 – 30.06.2023

I could previously identify resident tissue macrophages (RTM) as anti-inflammatory protectors of stromal integrity. The molecular mechanisms that regulate this tissue-protective function, however, are unknown. My preliminary work strongly suggests that within stromal tissues exist extensive, heterocellular communication networks. I hypothesize that functional network communication between stromal fibroblasts and RTM coordinate biological behavior of tissues and facilitate RTM functionality.

Principal Investigator
Dr. Stefan Uderhardt
phone: +49 9131 85-45487
e-mail: Stefan.Uderhardt@uk-erlangen.de

J90: Darja Andreev, Department of Medicine 3
The impact of Eos on bone loss

Main Research: Immunology and Infection

Term: 01.01.2022 – 30.06.2024

A healthy skeleton relies on a balance between bone-forming osteoblasts and bone-resorbing osteoclasts. A shift towards increased osteoclast activity can therefore lead to bone loss. The immune system strongly affects osteoclast biology, usually promoting osteoclast development. Interestingly, we demonstrated that eosinophils negatively regulate osteoclast formation and activity. Thus, it is of high relevance to unveil the molecular mechanisms underlying this regulatory function of eosinophils.

Principal Investigator
Dr. Darja Andreev
Phone: +49 9131 85-29291
Email: darja.andreev@uk-erlangen.de

J91: Jean-Philippe Auger, Department of Medicine 3
Glucocorticoid-induced macrophage reprogramming

Main Research: Immunology and Infection

Term: 01.01.2022 – 30.06.2024

Glucocorticoids are amongst the most important anti-inflammatory drugs, promoting inflammatory resolution via the functional reprogramming of macrophages, a process that promotes itaconate production. Though itaconate is an metabolite participating in immune-metabolic rewiring, its role and effects, as with the underlying mechanisms involved in its production, on immunometabolism and inflammatory resolution remain unknown, yet could contribute to further optimizing glucocorticoid treatment.

Principal Investigator
Dr. Jean-Philippe Auger
Phone: 09131 85-39313
Email: Philippe.Auger@extern.uk-erlangen.de
Universitätsklinikum Erlangen
IZKF Administrative Office

Krankenhausstr. 12
91054 Erlangen
  • Download-Center
  • Events
  • Contact
  • Imprint
  • Privacy
  • Facebook
  • RSS Feed
  • Twitter
  • Xing
Up