Renal and Vascular Research
Main Research: Renal and Vascular Research
Term: 01.10.2018 – 31.03.2021 (bonus time until 30.09.2021)
The genetic background of chronic kidney disease in adults in poorly investigated. This study aims to identify novel candidate genes by Whole Exome Sequencing in adult patients with chronic kidney disease. Transcriptome analysis of patient specific primary cells will be employed to functionally characterize these candidate genes. CRISPR/Cas9 based zebrafish experiments will transfer the in vitro findings in an animal disease model.
Dr. Tilman Jobst-Schwan