Archive IZKF-Projects

A37: Becker
Caspase-8 mediated regulation of intestinal epithelial cells in inflammatory bowel diseases
Term: 01.11.2010 – 31.10.2013

A38: Hildner, Atreya
Molecular and functional studies on the role of mucosal CD103+DCs during intestinal inflammation and infection
Term: 01.10.2010 – 30.09.2013

A39: Neufert, Becker
Differentiation and pathogenic role of Th17 cells in inflammatory bowel disease
Term: 01.10.2010 – 30.09.2013

A40: Distler, Schett
Canonical Wnt Signaling in the Pathogenesis of fibrotic diseases
Term: 01.12.2010 – 30.11.2013

A41: Herrmann, Munoz
The molecular mechanism of inflammation in crystal arthropathies
Term: 01.01.2011 – 31.12.2013

A42: Ullrich
Phenotypical and functional characterization of human NK cell subsets in different organs
Term: 15.10.2010 – 14.04.2013

A43: Stürzl
Systematic analysis of paracrine mechnisms in HHV-8-regulated tumorigenesis of Kaposi’s sarcoma
Term: 15.02.2011 – 14.02.2014

A44: Ensminger
Direct impact of human platelets in the formation of transplant arteriosclerosis
Term: 01.10.2010 – 31.03.2013

A45: Amann
Podozyten als nicht-hämatopoetische Antigen-präsentierende Zellen
Term: 01.11.2010 – 30.10.2013

A46: Lechmann
Role of the Cytokine TSLP in the pathology of Th1/Th17- and Th2- mediated immune reactions
Term: 20.01.2011 – 19.01.2014

A48: Mattner
Development of New Diagnostic Tools for Primary Biliary Cirrhosis
Term: 01.01.2011 – 31.12.2013

A49: Schleicher, Bogdan
Pharmaceutical sodium chlorite as a new therapeutic approach in cutaneous leishmaniasis: clinical efficacy and molecular mechanisms
Term: 01.03.2011 – 31.08.2013

A50: Schmidt
Search for new intrinsic restriction factors of HIV-1
Term: 01.10.2010 – 31.03.2013

A51: Stamminger
Cytomegalovirus encoded G-protein coupled receptors as novel targets for antiviral therapy
Term: 01.01.2011 – 30.06.2013

A52: Günther, Becker
Analysis about the functional role of cFLIP isoforms in intestinal epithelial cells
Term: 01.11.2013 – 31.10.2016

A53: Hildner
Molecular mechanisms of Th17 and piTreg differentiation in vivo
Term: 01.10.2013 – 30.09.2016

A54: Wirtz, Waldner
Fam180A: A new important mediator of inflammatory diseases?
Term: 01.11.2013 – 31.10.2016

A55: Krönke
The nuclear receptor NR4a1 as modulator of immunologic self tolerance
Term: 01.01.2014 – 31.12.2016

A56: Warnecke
Role of HIG2 in atherosclerosis
Term: 01.03.2014 – 28.02.2017

A57: Distler, Spriewald
Nr4a1as a novel target for the treatment of sclerodermatous chronic graft-versus-host disease 
Term: 01.01.2014 – 31.12.2016

A58: Mackensen, Völkl
Characterization of DN T cells from ALPS patients
Term: 01.10.2013 – 30.09.2016

A59: Finotto
Immunosuppressive role of IL-10 in lung cancer
Term: 01.10.2013 – 30.09.2016

A60: Baur, Schierer
Monocyte-derived Dendritic Cells (Mo-DC) by DC-Exosomes
Term: 01.10.2013 – 30.09.2016

A61: Bogdan, Schleicher
Cross-regulation of inducible NO synthase and iron in cutaneous and visceral leishmaniasis
Term: 01.02.2014 – 31.01.2017

A62: Stamminger
ND10 and interferon-induced gene expression
Term: 01.01.2014 – 31.12.2016

A63: Bogdan
Mechanisms of antimicrobial defense by TNF
Term: 01.07.2016 – 30.06.2019

A64: Distler, Schett
SHP2 as a target for the treatment of fibrosis
Term: 01.02.2016 – 31.01.2019

A66: Ensser
Identification of antiviral restriction factors
Term: 01.07.2016 – 30.06.2019

A65: Dudziak
Tolerizing potential of human DC subsets
Term: 01.04.2016 – 31.03.2019

A67: Gramberg
TRIM5alpha blocks LINE-1 retroelements
Term: 01.02.2016 – 31.01.2019

A68: Krönke, Nimmerjahn
Control of IgG activity by Th17 cells
Term: 16.06.2016 – 15.06.2019

A69: Lang
ATM/DDR in infection and inflammation
Term: 01.07.2016 – 30.06.2019

A70: Schubert
DUB-Inhibitoren and HIV-1
Term: 01.07.2016 – 30.06.2019

A71: Stamminger
Viral modulation of the protein kinase ULK1
Term: 01.07.2016 – 31.12.2018

A72: Steinkasserer
Modulation of Tregs and underlying mechanisms
Term: 01.07.2016 – 30.06.2019

A73: Überla
Checkpoint inhibitors as adjuvants
Term: 01.07.2016 – 30.09.2019

A74: Vöhringer, Krappmann
Eosinophils and ABPA
Term: 01.06.2016 – 31.05.2019

A75: Wirtz, Günther
MLKL-dependent necrosis in hepatitis
Term: 01.07.2016 – 30.06.2019

A81: Ensser
Receptor and neuropathogenicity of Bornavirus
Term: 01.01.2020 – 15.12.2022

A83: Gramberg
The role of SAMHD1 in CMV/ HIV coinfections
Term: 01.01.2020 – 31.12.2022

A85: Hüffmeier
The pathophysiology of SAPHO syndrome
Term: 01.06.2020 – 30.11.2022

A90: Tenbusch
The fate of lung-resident memory T-cells
Term: 01.01.2020 – 31.12.2022

D16: Wirtz
The role of IL-33/ST2 signalling in the pathogenesis of hepatic fibrosis
Term: 01.11.2010 – 31.10.2013

D17: Neipel
The role of Ephrin-A2 receptor-tyrosinkinase  in human herpesvirus-8 infection
Term: 01.10.2010 – 30.09.2013

D18: Schneider-Stock
Role of miRNAs in normal and malignant intestinal epithelial cells
Term: 15.10.2010 – 14.04.2013

D19: Becker
Role of intestinal epithelial SMAD7 for tumor development
Term: 01.11.2013 – 31.10.2016

D20: Stürzl, Croner, Naschberger
Collagen 10 and Metastasis in CRC
Term: 01.11.2013 – 31.10.2016

D21: Schneider-Stock, Neufert
Significance of Death-associated protein kinase (DAPK) in colorectal carcinogenesis
Term: 16.10.2013 – 15.10.2016

D22: Behrens
Identification and functional characterisation of novel components of the Wnt/β-catenin signal transduction pathway
Term: 01.11.2013 – 31.10.2016

D23: Bozec
Adipocytes in experimental bone metastasis
Term: 01.01.2016 – 31.12.2018

D24: Bosserhoff, Wegner
Schwann cell-associated proteins in melanoma
Term: 01.06.2016 – 31.05.2019

D25: Brabletz
Interaction of EGFR- and ZEB1 in cancer
Term: 01.05.2016 – 30.04.2019

D26: Mackensen, Fasching
TILs in triple-negative breast cancer
Term: 01.01.2016 – 31.12.2018

D27: Mougiakakos
2-HG as an Onco- and Immunometabolite in AML
Term: 01.07.2016 – 30.06.2019

D28: Stürzl, Naschberger
SPARCL1 in colorectal carcinoma
Term: 01.02.2016 – 31.01.2019

D29: Waldner
Aging of the immune system in CRC
Term: 01.01.2016 – 21.12.2018

D31: Bosserhoff
Modulation of oncogene-induced senescence
Term: 16.03.2020 – 15.03.2023

D35: Schödel
Interactions of DPF3 and hypoxia in renal cancer
Term: 01.07.2020 – 31.12.2022

E7: Schulze, Hess
Disordered synaptic signal transmission in the central nervous system – implications for tinnitus
Term: 01.01.2008 – 30.09.2012

E8: Mielenz
Swiprosin-1/EFhd2: mediator of neurodegenerative tauopathies?
Term: 01.10.2010 – 30.09.2013

E9: Winkler, Klucken, Wegner
The role of glial cells in synucleinopathies
Term: 01.10.2010 – 30.09.2013

E10: Eulenburg, Grömer
The role of neuronal glycine transporter 1 (GlyT1) in synaptic transmission
Term: 01.04.2011 – 30.09.2013

E11: Klucken, Xiang
Oxidative stress-mediated posttranslational modification of alpha-synuclein: The role of His50 of alpha-synuclein in Parkinson disease
Term: 01.12.2013 – 30.11.2016

E12: Winkler, Lie
Adult hippocampal neurogenesis in synucleinopathies
Term: 01.04.2014 – 31.03.2017

E13: Kornhuber, Müller, Reichel
Sphingomyelinase, depression and alcoholism
Term: 01.04.2014 – 31.03.2017

E14: Zimmermann
Role of TRPC5 in trigeminal nociception
Term: 01.04.2014 – 31.03.2017

E15: Eulenburg, Schulze
Glycine dependent neurotransmission and neuropathic pain
Term: 01.11.2013 – 31.10.2016

E16: Lie, Reis
Regulatory Networks in Intellectual Disability
Term: 01.04.2014 – 31.03.2017

E17: Hashemolhosseini
The neuromuscular role of Wnt signaling pathways
Term: 01.04.2014 – 31.03.2017

E18: Wegner, Winkler
Assessing developmental potential and differentiation capabilities of NG2-positive cells in the healthy and diseased central nervous system
Term: 01.12.2013 – 30.11.2016

E19: Enz
Inhibitory neurotransmission in the cochlea: Glutamate and endocannabinoids
Term: 15.02.2016 – 14.02.2019

E20: Kremer, Zimmermann
Identification of molecules, receptors and genes involved in chronic pruritus
Term: 01.05.2016 – 30.04.2019

E21: Lie, Klucken
FoxOs and alpha-Synuclein pathology
Term: 01.05.2016 – 30.04.2019

E22: Müller, Alzheimer, Mielenz
Swiprosin-1/EFhd2 in resilience to drug addiction
Term: 01.03.2016 – 28.02.2019

E23: Schlötzer-Schrehardt, Reis
LOXL1-SNPs in pseudoexfoliation syndrome/glaucoma
Term: 01.01.2016 – 31.12.2018

E24: Winkler, Linker
a-synuclein during inflammatory demyelination
Term: 01.01.2016 – 31.12.2018

E25: Winner, Schüttler
Human nociceptors
Term: 01.07.2016 – 30.06.2019

E26: Zweier
Intellectual disability with microcephaly
Term: 01.03.2016 – 28.02.2019

E27: Kremer
LPA-induced pruritus of cholestasis
Term: 01.03.2016 – 28.02.2019

E31: Zweier
Proteasomal degradation in intellectual disability
Term: 01.01.2020 – 31.08.2021

F1: Amann, Hilgers
Pathomechanisms and modulation of impaired angiogenesis and angioadaption in chronic renal failure
Term: 01.01.2011 – 30.06.2013

F2: Maas, König, Jacobi
AGXT2 – characterisation of an alternative route of metabolism for toxic methylarginines
Term: 01.10.2010 – 31.09.2013

F3: Engel
Fam60a in Heart and Brain Development
Term: 01.03.2014 – 28.02.2017

F4: Thiel
Pathogenesis of the Short rib-Polydactyly syndrome
Term: 01.10.2013 – 30.09.2016

F5: Buchholz
The Role of ANO1 in Polycystic Kidney Disease
Term: 01.07.2016 – 31.12.2018

F6: Veelken, Amann
Afferent renal nerves
Term: 01.07.2016 – 30.06.2019